About the PI
Peng Wu
Peng Wu is a Professor in the Department of Molecular Cell and Biology. Before joining the faculty at Scripps Research, Peng was an Associate Professor of Biochemistry and the Scientific Director of the Chemical Biology Core Facility at Albert Einstein College of Medicine, New York.
Peng Wu received his doctorate from Scripps Research in 2005 under the guidance of Professor K. Barry Sharpless. From September 2004 to early 2005, he was a visiting student in the laboratory of Professor Craig J. Hawker at IBM Almaden Research Center and at the University of California, Santa Barbara. His graduate studies, in collaboration with the Hawker lab, demonstrated for the first time the powerful utilization of click chemistry in the preparation of well-defined macromolecules and nanostructured materials.
From August 2005 to September 2008, Peng was a postdoctoral fellow in the group of Professor Carolyn R. Bertozzi at the University of California, Berkeley. There, he combined his interests in bioorthogonal chemistry and biotechnology by developing a method for site-specific modification of monoclonal antibodies using a genetically encoded aldehyde tag.
Research in the Wu lab integrates synthetic chemistry with glycobiology to explore the cellular and molecular mechanisms that control immune responses toward cancer and human pathogens. The primary goal of the laboratory is to develop chemical biology platforms to engineer cell-surface glycans for the study and tuning of the immune system. The laboratory is also interested in chemical tools that enable the selective enrichment of glycoproteins in leukocytes for their molecular identification and functional studies. These new tools will facilitate the discovery of new biomarkers for human disease and aid in the development of clinical diagnostics and therapeutics.
Team
Dedication. Expertise. Passion.
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Lab Alumni:
Postdoctoral Fellows
Dr. Zilei Liu (2017 – 2021)
Associate Director (Tech Dev), ImmunoScape, San Diego, CA
Dr. Senlian Hong (2017 – 2021)
Assistant Professor, School of Pharmaceutical Sciences, Peking Unviersity
Dr. Mingkuan Chen (2016 – 2020) Postdoctoral Researcher
Sanford Burnham Prebys Medical Discovery Institute
Dr. Jie Li (2015 – 2020) Joint with Sharpless Lab
Professor of Chemistry, Nanjing University
Dr. Yi Yang (2017 – 2020)
CEO, Glycotherapy
Dr. Aime Lopez Aguilar (2016 – 2018)
Assurex Health/Myraid Genetics- Miami, Florida
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Dr. Jennie Briard Depatie (2016 – 2017)
Miltenyi Biotec, Medical Science Liaison
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Dr. Yiran Zhou (2015 – 2017)
Sorrento Valley Therapeutics
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Dr. Lei Feng (2010 – 2016)
Assistant Director, Kodikaz Therapeutic Solutions, Inc
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Dr. Hao Jiang (2010 – 2015)
Associate Professor, Ocean University of China
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Dr. Wei Wang (2015 – 2017)
Chem-Master, Inc., Scientist
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Dr. David Soriano del Amo (2008 – 2011)
Acellera, Business Development Associate
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Staff Scientist
Dr. Hua Wang (2018)
Sorrento Therapeutics, Inc., Director
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Research Technicians
Angel Gandrarilla (2008)
Xiaomeng Hou (2016 – 2017)
Linda Zhang (2016 – 2017)
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Research Assistants
Brandon Dinner (2021 – 2022)
Natalie R (2018 – 2023)
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Graduate Students
Dr. Zhou Yang (2019 – 2023)
Senior Scientist at AstraZeneca Biologics Engineering Department
Dr. Tianqing Zheng (2008 – 20213)
Post-doctoral Fellow at University of Iowa and HHMi
Dr. Sara Rouhanifard (2010 – 2014)
Assistant Professor at Northeastern University
Dr. Abubaker Jalloh (2010 – 2016)
Scripps Research, Corporate Development Assoc. Director
Dr. Christen Besanceney (2008 – 2012)
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Undergraduate Students
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Ruitong Li
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Qi Kong
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Jiaqi Chen
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Yuning Zhang
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Rebecca Triano
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Yizheng He
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Pepsi Mock
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Yujia Wang
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Haoran Pang
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Andrew Tran
Student Research Intern
Daniel Toobian, University of California San Diego
Nicole Chang
Emily Yang